Organic Reaction in Water. Part 31: Diastereoselectivity in Michael Additions of Thiophenol to Nitro Olefins in Aqueous Media
نویسندگان
چکیده
Tiofenóis reagem com nitro olefinas em meio aquoso dando os correspondentes nitro-sulfetos em 58 95 % de rendimento. Este processo leva à formação, predominante, de produtos anti. Para o caso da nitro olefina cíclica 1-nitro-ciclo-hexeno é observada unicamente a formação de cis-1nitro-2-(tio-fenil)-ciclo-hexano. Esta metodologia é interessante porque utiliza-se água como solvente levando à minimização do custo, diminuindo os problemas de toxidez e poluição ambiental
منابع مشابه
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